Opioid Induced Constipation Market $3.93 Bn By 2032, CAGR 4.6%

Opioid Induced Constipation Market Size Worth $3.93 Billion By 2032 | CAGR: 4.6%

The global opioid induced constipation market size is expected to reach USD 3.93 billion by 2032, according to a new study by Polaris Market Research. The report “Opioid Induced Constipation Market Share, Size, Trends, Industry Analysis Report, By Active Ingredients; By Prescription Type; By Route of Administration; By Distribution Channel; By Region; Segment Forecast, 2024 - 2032” gives a detailed insight into current market dynamics and provides analysis on future market growth.

Opioids are most used to get relief from pain, as they include morphine, tramadol, and fentanyl. The increased accessibility of painkillers at retail and online e-commerce platforms is showing a positive impact on the demand for opioids in the marketplace, including significant growth potential for opioid-induced constipation.

The rising awareness campaigns by pharmaceutical companies, governments, and non-government agencies are demonstrating a positive impact on the opioid-induced constipation market. For instance, in 2023, Salix Pharmaceuticals, a drug manufacturer, along with the other two non-profit organisations, declared December 5 as the opioid-induced constipation awareness day to confront the stigmas surrounding the issue.

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The rising use of opioids among the larger consumer base is expected to boost demand for opioid-induced constipation treatment. According to the available data, among the individuals who consumed opioids without cancer, around 40–60% of the people get opioid-induced constipation (OIC). 

The higher risk of constipation with the intake of opioid-related drugs, along with the growing research studies to review the potential causes and suitable treatments, are showing wider growth opportunities for the market. For instance, a study published in the National Library of Medicine explored opioid-induced constipation and reviewed potential therapeutic and non-therapeutic treatments to treat the disease.

Furthermore, the use of opioids can be related to the rising use by cancer patients to get pain relief. According to pharmaceutical experts, approximately 60 to 90% of patients who took the opioid for cancer treatment suffered from opioid-induced constipation. Opioid-induced constipation patients are likely to face more difficulties in day-to-day life activities, primarily those facing cancer pain.

Moreover, research activities are positively influencing the creation of effective treatments for patients suffering from opioid-induced constipation. For instance, a 2024 study focused on finding the relationship between opioid-induced constipation and the P2Y1 receptor in the colonic myenteric plexus of rats.

Opioid Induced Constipation Market Report Highlights

  • Naloxegol segment will grow at the fastest pace, due to its potential for treating opioid induced constipation issues.
  • Prescription segment held the largest share, owing to the rising importance of doctor consultation.
  • Oral segment dominated the market, primarily due to its ease of treatment intake and higher effectiveness.
  • Asia Pacific will register the fastest pace, attributable to the presence of the large proportion of elderly population.
  • The global players include Abbott, Aurobindo Pharma, Bayer, Boehringer Ingelheim International, & Bristol Myers Squibb Company.

Polaris Market Research has segmented the opioid induced constipation market report based on active ingredients, prescription type, route of administration, distribution channel and region:

Opioid Induced Constipation, Active Ingredients Outlook (Revenue - USD Billion, 2019 - 2032)

  • Naloxegol
  • Lubiprostone
  • Methylnaltrexone Bromide
  • Docusate Sodium
  • Others

Opioid Induced Constipation, Prescription Type Outlook (Revenue - USD Billion, 2019 - 2032)

  • Over The Counter Medicines
  • Prescription, Natural Remedies

Opioid Induced Constipation, Route of Administration Outlook (Revenue - USD Billion, 2019 - 2032)

  • Oral
  • Injectable
  • Others

Opioid Induced Constipation, Distribution Channel Outlook (Revenue - USD Billion, 2019 - 2032)

  • Hospital Pharmacy
  • Online Pharmacy
  • Retail Pharmacy

Opioid Induced Constipation, Regional Outlook (Revenue - USD Billion, 2019 - 2032)

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Russia
    • Netherlands
  • Asia Pacific
    • China
    • India
    • Japan
    • South Korea
    • Indonesia
    • Malaysia
  • Latin America
    • Argentina
    • Brazil
    • Mexico
  • Middle East & Africa
    • UAE
    • Saudi Arabia
    • Israel
    • South Africa

Opioid Induced Constipation Market Report Scope

Report Attributes


Market size value in 2024

USD 2.74 billion

Revenue forecast in 2032

USD 3.93 billion


4.6% from 2024 – 2032

Base year


Historical data

2019 – 2022

Forecast period

2024 – 2032

Quantitative units

Revenue in USD billion and CAGR from 2024 to 2032

Segments covered

  • By Active Ingredients
  • By Prescription Type
  • By Route of Administration
  • By Distribution Channel
  • By Region

Regional scope

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

Competitive Landscape

  • Opioid Induced Constipation Market Share Analysis (2023)
  • Company Profiles/Industry participants profiling includes company overview, financial information, product/service benchmarking, and recent developments

Report Format

  • PDF + Excel


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