Oligonucleotide Synthesis Market Size Worth $10.17 Billion By 2032 | CAGR: 12.55%

Oligonucleotide Synthesis Market Size Worth $10.17 Billion By 2032 | CAGR: 12.55%

The global oligonucleotide synthesis market size is expected to reach USD 10.17 billion by 2032, according to a new study by Polaris Market Research. The report “Oligonucleotide Synthesis Market Share, Size, Trends, Industry Analysis Report, By Product (Synthesized Oligonucleotide Products, Equipment, Reagents, Equipment, and Services); By Application; By Region; Segment Forecast, 2024- 2032” gives a detailed insight into current market dynamics and provides analysis on future market growth.  

Oligonucleotide therapeutics exhibit substantial promise in addressing chronic conditions such as retinal disorders, cancers, and cardiovascular, among others. The continuous evolution and newfound implementation of oligo sequences across various biotechnological domains are anticipated to propel market expansion. A significant upsurge in demand for molecular diagnostics, especially in precision care, stands out as a crucial emerging application for oligonucleotide synthesis.

The integration of advanced methodologies such as high-throughput sequencing and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) for gene expression analysis has streamlined genome modification and genetic screening, thereby influencing the demand for oligonucleotide synthesis. Manufacturers are actively investing in technology development to facilitate the production of longer oligonucleotides with enhanced precision and higher yield, aligning with the increasing demand for customized oligos.

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The pivotal driver behind oligonucleotide synthesis market growth lies in the presence of a regulatory framework supportive of genomic advancements. Anticipated changes in regulatory policies aimed at creating a well-defined environment for advanced biological research and its application in human use are poised to exert a substantial impact on the demand for oligonucleotide synthesis. Healthcare sectors, particularly in stem cells, regenerative medicine, genetic engineering, and synthetic biology, are identified as key areas with significant potential. An illustrative example is the International Society for Stem Cell Research (ISSCR) ethics and public policy committee, which endeavors to address concerns through transparent discussions. This committee, comprising global experts in ethics, law, and social policy, plays a vital role in recognizing and resolving pertinent issues.

Moreover, the market undergoes rigorous regulatory scrutiny, particularly in the clinical applications of genomics, where stringent monitoring and restrictions prevail in many countries. Some jurisdictions permit genetic research in non-human use sectors. Anticipated shifts in regulatory policies geared towards establishing a well-defined framework for advanced biological research and its application in human use are poised to exert a substantial impact on the demand for oligonucleotide synthesis. These changes reflect the dynamic landscape of regulatory considerations, affecting the market's trajectory and emphasizing the need for compliance and adaptability in the evolving field of genomics.

Oligonucleotide Synthesis Market Report Highlights

  • In 2023, the synthesized oligonucleotide products segment is expected to witness highest growth during forecast period owing to increased prevalence of genomic studies
  • PCR primers segment is expected to dominate the oligonucleotide synthesis market during forecast period. This is attributed to increase in detecting and measuring gene expression
  • In 2023, North America accounted for the largest revenue share due to presence of major players, technological advancements, and growing awareness of genetic disorders.
  • The market is highly competitive owing to the existence of market players with a global presence, including ATDBio Ltd., Bio-Synthesis Inc., Biosearch Technologies, Eurofins Genomics, GE Healthcare, among others.

Polaris Market Research has segmented the oligonucleotide synthesis market report based on product, application, and region:

Oligonucleotide Synthesis, Product Outlook (Revenue - USD Billion, 2019 - 2032)

  • Synthesized Oligonucleotide Products
  • Equipment
  • Reagents
  • Services

Oligonucleotide Synthesis, Application Outlook (Revenue - USD Billion, 2019 - 2032)

  • PCR Assays and Panels
  • PCR Primers
  • DNA Microarrays
  • Sequencing
  • Antisense Oligonucleotides
  • Fluorescence In Situ Hybridization (FISH)
  • Others

Oligonucleotide Synthesis, Regional Outlook (Revenue - USD Billion, 2019 - 2032)

  • North America
  • U.S.
  • Canada
  • Europe
  • France
  • Germany
  • UK
  • Italy
  • Netherlands
  • Spain
  • Russia
  • Rest of Europe
  • Asia Pacific
  • Japan
  • China
  • India
  • Malaysia
  • Indonesia
  • South Korea
  • Australia
  • Rest of APAC
  • Latin America
  • Brazil
  • Mexico
  • Argentina
  • Rest of LA
  • Middle East & Africa
  • Saudi Arabia
  • UAE
  • Israel
  • South Africa
  • Rest of MEA

Oligonucleotide Synthesis Market Report Scope

Report Attributes


Market size value in 2024

USD 3.95 billion

Revenue forecast in 2032

USD 10.17 billion


12.55% from 2024 – 2032

Base year


Historical data

2019 – 2022

Forecast period

2024 – 2032

Quantitative units

Revenue in USD billion and CAGR from 2024 to 2032

Segments covered

  • By Product
  • By Application
  • By Region

Regional scope

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

Competitive Landscape

  • Oligonucleotide Synthesis Market Share Analysis (2023)
  • Company Profiles/Industry participants profiling includes company overview, financial information, product/service benchmarking, and recent developments

Report Format

  • PDF + Excel


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