U.S. Phosphoramidite Market Size Worth USD 843.12 Million by 2034 | CAGR: 7.9%

The US Phosphoramidites Market size is expected to reach USD 843.12 Million by 2034, according to a new study by Polaris Market Research. The report “U.S. Phosphoramidite Market Share, Size, Trends, Industry Analysis Report: By Type (DNA Phosphoramidites, RNA Phosphoramidites), By Application, By End User, and By Country; Market Forecast, 2025–2034” gives a detailed insight into current market dynamics and provides analysis on future market growth.

The demand for phosphoramidites in the U.S. is growing due to their extensive use in therapeutic research, molecular diagnostics, gene editing, and synthetic biology. High-purity DNA and RNA phosphoramidites support oligonucleotide synthesis, enabling cost-effective drug development and precision medicine applications.

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Market growth is driven by increasing adoption of customized phosphoramidite derivatives, high-throughput automated synthesis platforms, and a rising focus on RNA therapeutics and CRISPR-based research. Technological advancements in reagent stability, yield optimization, and digital process integration help manufacturers meet diverse R&D requirements while ensuring regulatory compliance.

Top of FormU.S. Phosphoramidite Market Report Highlights

• Based on type, the DNA phosphoramidites segment dominated the market in 2024 due to widespread use in therapeutic research, RNA interference, and molecular diagnostics.
• Based on application, drug discovery and development held the largest share in 2024, driven by its extensive use in preclinical and clinical research pipelines.
• In terms of end users, pharmaceutical and biotechnology companies dominated the market in 2024, while academic and research institutes are projected to grow at the fastest rate.
• A few global key market players include Glen Research, TriLink BioTechnologies, Thermo Fisher Scientific, ChemGenes Corp., Biosynth Carbosynth, BOC Sciences, emp BIOTECH, Lumiprobe, Hunan Honya Biotech Co., Ltd., GenScript, Integrated DNA Technologies, Inc., and Merck KGaA.

Polaris Market Research has segmented the market report on the basis of type, application, end user, and country:

By Type Outlook (Revenue, USD Million, 2020–2034)

• DNA Phosphoramidites
• RNA Phosphoramidites
• Labeled Phosphoramidites
• Modifier Phosphoramidites
• Other Types

By Application Outlook (Revenue, USD Million, 2020–2034)

• Drug Discovery & Development
• Diagnostics Development
• Gene Editing & Synthetic Biology
• Other Applications

By End User Outlook (Revenue, USD Million, 2020–2034)

• Pharmaceutical and Biotechnology Companies
• Academic and Research Institutes
• Other End Users