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CAR T Cell Therapy Market

CAR T Cell Therapy Market [By Target Antigen (CD19, CD20, MESO, HER2, EGFRV III, and Others); By Application (Acute Lymphoblastic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Chronic Lymphocytic Leukemia, Multiple Myeloma, and Others); and By Regions]: Market size & Forecast, 2018 – 2025

Published: Sep 2018
Pages: 120
Format: PDF
Report ID: PM1389
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Report Summary

The worldwide CAR T Cell Therapy Market was estimated at USD 149.3 Million in 2017, expected to grow at 45.6% CAGR by 2025. CAR-T (Chimeric Antigen Receptor) cell therapy comprises re-engineering cancer patient's white blood cells (WBC) to fight the malignant cells by recognizing them. During this therapy, the person’s T cells are extracted, preciously reformed and then inserted again to the person's body where the restructured cell multiply and target cancer cells. Currently, CAR T cell therapy is recognized as vastly effective in patients with blood cancer who are already gone through alternative cancer treatment therapies such as chemotherapy.

CAR-T is a revolutionary advanced technology that involves a unique business model in R&D as well as pharmaceutical industries. Increasing levels of acquisitions as a part of innovative research and the increasing importance of cellular therapies are estimated to significantly boost the market growth.  For instance, as per the current market scenario, Novartis and Gilead are leading key players of CAR-T with their first therapies approved in pediatric Acute Lymphoblastic Leukemia (ALL) and adult Diffuse Large B-cell Lymphoma (DLBCL). Moreover, Celgene is also associating with Bluebird Bio and are expected to carry the first in class B-cell maturation antigen (BCMA) CAR-T for Multiple Myeloma to market up to 2020.

Figure - CAR-T Cell Therapy Market Share Value, By Application, 2025

CAR T cell therapy market

Increasing number of patients presenting a failure response to alternative therapies and growing occurrence of cancer cases are expected enhance the growth of the global CAR-T cell therapy market. High cancer cases are anticipated to increase the demand for reliable and effective therapeutic treatment approach for enhancement of quality of person’s life. However, complexity associated with manufacturing process, high costs as well as life-threatening toxicity are some of the factors estimated to hinder the market growth.

Modern Market Scenario

In 2018, CAR T therapies are estimated to be the highly significant market as being such flattering as well as the relevant theme for researchers and investors. CAR-T is at the leading stage of cellular therapies, with additional methodologies with its similar challenges and promises. It is expected to remark the new insights and products on the viable capability as more patients are treated in a commercial setting. Such therapies are estimated to generate a vast revolution in the oncology sector, complementary to the ongoing breakthrough of immuno-oncology.

Segment Analysis

The Global CAR T Cell Therapy Market is segmented on the basis of target antigen, application, and geography.

Figure - CAR T Cell Market Segmentation

CAR-T-Cell-Market-Segmentation

On the basis of application, the therapy for Diffuse Large B-Cell Lymphoma (DLBCL) was estimated to be the largest market sharing segment followed by multiple myeloma. In addition, Chronic Lymphocytic leukemia and follicular lymphoma are expected to be the major market segments during the forecast period. The first therapy approved was in pediatrics and/or young adults Acute Lymphoblastic leukemia (ALL), an ailment with a high unmet need where CAR-T indicated high effectiveness, nonetheless, which represents a very small patient population.

Regional Analysis

In terms of geography, North America was estimated to dominate the global CAR T Cell Therapy Market. Increasing research and developments programs as well as ongoing regulatory approvals are factors attributed to the augmented market growth for CAR T cell therapy. For instance, Kymriah (a Novartis product) has cleared the USFDA approval in August 2017 for the treatment of patients suffering from acute lymphoblastic leukemia. Moreover, according to an industry report, key players such as Novartis and Kite are the first to reach the US market and are anticipating to focus on expanding the number of academic centers that can provide appropriate cancer treatments in 2018.

Figure - North America Estimated CAR T Cell Therapy Market Size & Forecast, 2018-2025

Competitive Landscape

Major companies are focusing on small firms with a working methodology of securing the end goal to manage position in the market and are associated with mergers and acquisitions, key joint efforts, and novel item advancement to pick up profit share in the business. Some major key players in global CAR T Cell Therapy Market includes Novartis International AG, Kite Pharma, Inc., Juno Therapeutics, Pfizer, Inc. Celgene Corporation, Cellectis, Sorrento Therapeutics, Bluebird bio, and Immune Therapeutics among others.

Key questions answered by the report

  • What is the current Market Size and Forecasts of CAR T Cell Therapy Market.
  • What is the market opportunity for CAR T Cell Therapy Market.
  • How big is the market size for consulting services for CAR T Cell Therapy Market.
  • How much is the estimated market for CAR T Cell Therapy in North America in the forecast period.
  • What are the available opportunities and who are the top market players in this space.
  • Which are the major target antigen segments and what traction are they gaining in the market.

 

Table of Contents

  1. Overview and Scope
    1. Research goal & scope
    2. Research assumptions
    3. Research Methodology
      1. Primary data sources
      2. Secondary data sources
    4. Key take-aways
    5. Stakeholders
  2. Executive Summary
    1. Market Definition
    2. Market Segmentation
  3. CAR T Cell Therapy Market Insights
    1. CAR T Cell Therapy– Industry snapshot
    2. CAR T Cell Therapy- Ecosystem analysis
    3. CAR T Cell Therapy Market dynamics
      1. CAR T Cell Therapy– Market Forces
        1. CAR T Cell Therapy Market driver analysis
        2. CAR T Cell Therapy Market restraint/challenges analysis
        3. CAR T Cell Therapy Market opportunity analysis
    4. Industry analysis - Porter's five force
      1. Bargaining power of supplier
      2. Bargaining power of buyer
      3. Threat of substitute
      4. Threat of new entrant
      5. Degree of competition
    5. CAR T Cell Therapy Market PEST analysis, 2017
    6. CAR T Cell Therapy Industry trends
    7. Competitive Ranking Analysis
  4. CAR T Cell Therapy Market Size and Forecast 2017 - 2025 by Target Antigen
    1. Key findings
    2. CD19
    3. CD20
    4. MESO
    5. HER2
    6. EGFRV III
    7. Others
  5.  CAR T Cell Therapy Market Size and Forecast 2017 - 2025 by Application
    1. Key findings
    2. Acute Lymphoblastic Leukemia
    3. Diffuse Large B-Cell Lymphoma
    4. Follicular Lymphoma
    5. Chronic Lymphocytic Leukemia
    6. Multiple Myeloma
    7. Others
  6. CAR T Cell Therapy Market Size and Forecast 2017 - 2025 by Regions
    1. Key findings
    2. North America
      1. U.S.
    3. Europe
    4. Asia Pacific
      1. China
  7. Company Profiles
    1. Novartis International AG
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    2. Kite Pharma, Inc.
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    3. Juno Therapeutics
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    4. Pfizer, Inc.
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    5. Celgene Corporation
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    6. Bluebird bio
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    7. Immune Therapeutics
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    8. Atara Biotherapeutics
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    9. CARsgen Therapeutics
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments
    10. Bellicum Pharmaceuticals, Inc.
      1. Overview
      2. Financials
      3. Product Benchmarking
      4. Recent Developments

Report Content

Qualitative Analysis

  • Industry overview
  • Industry trends
  • Market drivers and restraints
  • Market size
  • Growth prospects
  • Porter’s analysis
  • PESTEL analysis
  • Key market opportunities prioritized
  • Competitive landscape
    • Overview
    • Financials
    • Product benchmarking
    • Latest strategic developments

Quantitative Analysis

  • Market size, estimates, and forecasts from 2017 to 2025
  • Market revenue estimates for target antigen up to 2025
  • Market revenue estimates for application up to 2025
  • Regional market size and forecast for target antigen from 2017 to 2025
  • Regional market size and forecast for application segments up to 2025
  • Company financials

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