U.S. Gout Therapeutics Market Size Worth USD 2.73 Billion by 2034 | CAGR: 6.9%

The U.S. gout therapeutics market size is expected to reach USD 2.73 billion by 2034, according to a new study by Polaris Market Research. The report “U.S. Gout Therapeutics Market Size, Share, Trend, Industry Analysis Report By Disease Condition (Acute Gout, Chronic Gout), By Drug Class, By Distribution Channel – Market Forecast, 2025–2034” gives a detailed insight into current market dynamics and provides analysis on future market growth.

The U.S. gout therapeutics market focuses on the development, distribution, and adoption of pharmaceutical solutions aimed at managing uric acid buildup and the associated inflammation that causes acute and chronic gout. The market is expanding due to the rising incidence of comorbid conditions such as obesity, hypertension, and metabolic syndrome, all of which increase gout risk. Demand is further strengthened by heightened awareness among both patients and providers regarding early diagnosis and sustained treatment. Strong reimbursement frameworks and access to specialty care support the uptake of biologics and next-generation urate-lowering agents. Market participants are actively investing in therapies that offer better tolerability, lower dosing frequency, and reduced cardiovascular risks. Industry trends point to a shift toward personalized care, emphasizing biomarkers and patient-specific therapeutic responses.

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The integration of digital health platforms into gout management is creating new channels for monitoring and adherence. Opportunities exist in expanding treatment access to underserved populations, improving disease education, and addressing medication non-compliance. Innovation in drug formulation, including oral biologics and dual-action therapies, is driving product differentiation. The increasing willingness among payers to reimburse high-cost but high-efficacy treatments reflects the demand for long-term cost containment through effective disease control. Clinical focus is shifting beyond flare reduction to long-term prevention and comorbidity management, positioning the market for continued innovation. Expansion into combination therapies, supported by strong post-market surveillance data, is expected to shape the future landscape. The market is aligning around outcomes-based value, driving both clinical and economic incentives for continued investment.

Top of FormU.S. Gout Therapeutics Market Report Highlights

• By drug class, the NSAIDs segment dominated the U.S. gout therapeutics market with ~43% of the revenue share in 2024 due to their rapid action in reducing inflammation and pain associated with acute gout flares
• Based on disease condition, the chronic gout segment held the largest revenue share in 2024 due to growing demand for long-term management therapies.
• A few key players include Arrowhead Pharmaceuticals, Inc.; AstraZeneca; GSK plc.; Eisai Co., Ltd.; Merck & Co., Inc.; Novartis AG; Regeneron Pharmaceuticals Inc.; Takeda Pharmaceutical Company Limited; Teijin Pharma Ltd.; and Zydus Group.

Polaris Market Research has segmented the market report on the basis of disease condition, drug class, and distribution channel:

By Disease Condition Outlook (Revenue, USD Billion, 2020–2034)

• Acute Gout
• Chronic Gout

By Drug Class Outlook (Revenue, USD Billion, 2020–2034)

• NSAIDs
• Corticosteroids
• Colchicine
• Urate-Lowering Agents
• Others

By Distribution Channel Outlook (Revenue, USD Billion, 2020–2034)

• Hospital Pharmacy
• Retail Pharmacy
• Online Pharmacy